The Soul of a Physician Innovator with Piyush Mathur, MD

Healthcare AI is no longer just about predictive models and dashboards. We are entering the age of autonomous agents — systems that don’t just analyze data, but reason, act, and collaborate within clinical workflows.

In this episode, we sit down with Piyush Mathur, MD, FCCM, FASA, FAMIA — Co-Founder of BrainX AI and BrainX Community, anesthesiologist and intensivist at the Cleveland Clinic — to explore what it truly takes to implement AI responsibly inside complex healthcare systems.

With more than 20 years of clinical experience and over a decade serving as Quality Improvement Officer and Compliance Committee Lead at Cleveland Clinic’s Anesthesiology Institute, Dr. Mathur brings a rare combination of frontline care, quality leadership, regulatory insight, and technical fluency. Trained in computer programming through Udacity’s Nanodegree program (with focus on data analysis, machine learning, and AI), he bridges the worlds of medicine, governance, and engineering.

In this conversation, we discuss:

• What…